Episode 6 of "On Call" kicks off with Harmon and Diaz intervening in a heated altercation between two individuals. The elderly gentleman accuses the youthful offender of speeding down the street and colliding with a stray dog. The younger man steadfastly denies any wrongdoing, yet there are no other eyewitnesses to corroborate either story. The poor dog, severely wounded, lies helplessly, and with animal control en route but unlikely to arrive in time, Sergeant Lasman declares euthanasia as the most humane solution. Harmon, unable to carry out the task, steps aside, leaving Lasman to perform the grim duty.
Following the incident, Diaz seeks forgiveness for his harsh words during their previous shift, and Harmon graciously accepts his apology. In a somber tone, Diaz reveals that his brother has been attacked by three inmates in prison. This revelation stirs Harmon's resolve, and she decides they should still approach Smokey, despite the daunting odds.
The duo heads to the bar, where Harmon inquires about the terms needed to secure their favor. However, they hit a dead end in negotiations, and even when Harmon volunteers to take responsibility, Smokey mocks, suggesting he finds more amusement in forcing her to watch . Diaz and Harmon depart, with Diaz visibly more distressed than ever, his frustration compounded by the confiscation of his phone, preventing him from reaching Gabriel.
Suddenly, their calm is shattered by an emergency call regarding three overdose victims at a party. Racing to the scene, they discover three minors who have overdosed on cocaine. Administering Narcan swiftly, they manage to stabilize the victims just before the paramedics arrive. Yet, a young girl teeters on the brink of life and death, requiring immediate resuscitation, leaving both officers haunted by the harrowing ordeal.
Diaz and Harmon proceed towards the homeless encampment, their steps laden with purpose. Harmon unfolds a tale of her sister's tragic descent into drug addiction following a devastating injury. Jen, now known ominously as The Sheriff, has become a shadow of her former self. When Harmon locates Jen, she conveys their mother's heartfelt plea for her return, her voice tinged with urgency.
The conversation quickly escalates into a heated debate as Harmon strives to persuade Jen to reclaim her place at home. Emotions flare, culminating in Harmon resorting to drastic measures – she handcuffs Jen and tasks Diaz with searching her. Diaz's search reveals no illicit substances, but instead, an unexpected relic: Jen's old police badge, a symbol of her bygone days of upholding the law.
Determined to rehabilitate her sister through confinement, Harmon considers arresting her. However, Diaz, who understands the devastating impact of incarceration on families, proposes an alternative. He suggests placing Jen in a safe haven, a sanctuary where he and his brother once refugied their mother after tumultuous encounters with abusive partners. Relenting, Harmon complies, depositing Jen at the safe house while retaining her badge, promising to restore it upon her reformation. Jen, compliant in her current state, nods in agreement.
As the dust settles, Harmon turns to Diaz, contemplating a strategic maneuver. She proposes leveraging a personal favour to relocate Gabriel to a facility beyond East Barrio's influence, a plan to sever his ties with the dangerous milieu. Diaz, considering the proposition, concurs that it might just work, his endorsement closing the chapter on Episode 6 of On Call with a glimmer of hope.