Amy Schumer is stealing the show with her unfiltered, candid weight loss journey. The comedian has been sharing snapshots of her toned physique, baring her midsection in a bathroom mirror selfie, declaring, "No filter, no filler," with a wry nod to the water stains on her reflection. The 44-year-old has been chronicling her body transformation through photos, recently showcasing her slimmer legs in a short, black Miu Miu dress during a girls' night out in Las Vegas. Her friends couldn't help but rave about her new look, with Kathy Griffin joking, "I'm so jealous of your legs, I can barely talk to you," while Lee Daniels quipped, "Skinnnnny mommmmma." Amy Sedaris added, "You look incredible. Look at those pins!!!"

But the road to her toned figure hasn't been without its challenges. Amy's journey with Ozempic—a type 2 diabetes drug some celebrities use to slim down due to its appetite-reducing properties—left her bedridden. "I was vomiting," she recounted during an appearance on The Howard Stern Show in January. "I was shriveling." In fact, Amy said she had "no energy" to play with her and husband Chris Fisher's 6-year-old son Gene while on the medication. "I'm in bed and my son's like, 'Can you play tag?'" she recalled. "And I'm like, 'I can’t.'"
Despite the setbacks, Amy believes it's best to be honest about her usage of the medication, which has not been approved by the FDA for weight loss purposes. "Everyone has been lying saying, 'Oh, smaller portions,'" she said on Watch What Happens Live with Andy Cohen in 2023. "Like, shut the f--k up. You are on Ozempic or one of those things, or you got work done. Just stop." The Trainwreck actress added, "Be real with the people. When I got lipo, I said I got lipo."